Year 5, Number 19, January 2003

 

Do children with aggressive behavior have temporal lobe changes?.

Article N° AJ19-3

 

 

Material and Methods


CLINICAL DATA

In addition to the referring physician’s clinical diagnosis, a questionnaire was routinely completed for each child by the parents. This was in a simple "yes" or "no" format, with opportunity for amplification or comment. One of the questions was, "Is there a problem with temper". All parents answered this question.

IMAGING

All eight patients had measurement of absolute mean cortical cerebral blood flow using Kanno and Lassen’s modification of Obrist’s method measuring regional washout of inhaled xenon-133 gas. (3,4) This was followed by intravenous injection of freshly prepared Tc 99m-HMPAO, with the patients in a resting state in a dim, quiet room. No sedation was used. High resolution brain SPECT Imaging was performed one hour post injection using the Picker 3000XP triple headed camera with fan beam collimators. The scan time was 20 minutes in the continuous mode; the matrix size was 128x128, angular range of 120 CCW, angular step 3.00, and 30 sec/step, 120 total acquisitions.

All the studies were processed using a preset brain program. Image attenuation correction was done using the Chang method, and reconstruction was performed using a Low Pass filter (Butterworth) with an order of 8.0 and a cut -off ranging between 0.20 and 0.23. We obtained a transverse, coronal and sagittal slices. A slice thickness of 2 pixels, 4.4 mm, was selected using the Picker preset program for oblique reformatting.

 


Summary | Background | Patient Population | Material and Methods | Analysis | Findings | Conclusion | References | Print

 

 

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