RAKIDUAM - Knowledge

The Center of Advanced Studies on Chronic Diseases (ACCDiS) focuses its research on cardiovascu- lar illnesses and cancer, with the objective of identifying their common elements, in order to offer solutions to the country’s health problems by collaborating in the diagnosis, prognosis, treatment and generation of public prevention policies. ACCDIS gathers over 220 members including academics, postdoctorate students, postgraduate students and undergraduate students, professionals and technicians, who carry out transdisciplinary research on issues such as molecules all the way through to public health. A significant contribution is the MAUCO Project, where 10,000 adults residing in the Region of Maule are assessed and followed for 10 years, and this is the first epidemiological cohort in Chile. In its third year of execution, the Center surpassed the productivity and quality targets proposed: with 145 publications in ISI-indexed magazines (average impact factor of 4.8; 24 of them in magazines of the upper 10% of the discipline and 61 in magazines of the 25%). ACCDiS is a benchmark in the formation of human resources with 25 postdoctorate students and 74 students doing their doctorate dissertations. The diffusion and extension of the Center is done for the scientific world as well as for the community in general, and carries out a variety of activities, in which more than 8,600 people have participated. ACCDiS also has a permanent and active presence in the national communication media. Hosting Institutions: Universidad de Chile and Pontificia Universidad Católica. Center of Advanced Studies on Chronic Diseases (ACCDiS) 25 Lines of Research Metabolism and cardiovascular signaling. Emerging Biomarkers in cardiac insufficiency. Inflammation in angiogenesis, cellular migration and metastasis. Biomarkers for the early detection of gastric tumors. Natural history of gallbladder cancer. Nanomedicine and nanotheranostics.